Manchester United versus Liverpool.
It is one of, if not, the biggest football game on the planet.
The rivalry will never settle down and if anything, it only gets worse.
If you are a fan of either one of these sides, you will probably start to feel sick around now just thinking of the fixture.
The humiliation of a loss
The jubilation of a win.
Contrasting emotions which can happen just due to one kick of a ball.
It is a sickening feeling but that is when you know it is special.
This season there is a different dimension to the game, and we all know who has brought it.
Cristiano Ronaldo.
One of the greatest of all time, he is built for the biggest games in the world and realistically it would be an astronomical surprise if he is not one of the reasons why the outcome of the match is what it is.
It is inevitable and it will be a pleasure for the neutral to see Ronaldo go up against Virgil Van Dijk for the fourth time in his career.
He is yet to score when facing Van Dijk and Liverpool fans will be hoping that continues as the positive atmosphere amongst the supporters is unsurprisingly very high due to The Reds still being unbeaten in all competitions.
There is some positive injury news for Liverpool as Curtis Jones is back in contention to play after suffering an injury on international duty.
However, Thiago Alcantara is expected to be out until just before the next international break which is a significant blow for Jurgen Klopp.
Other than that though, there is no fresh injury concerns which means Mohamed Salah will be fit and ready to try to carry on his exceptional form.
The pre-match build-up is already circulating around the Salah and Ronaldo show.
Which is no real surprise.
Klopp had his say in the press conference as the German said: “Why should we compare?
“Both are world-class. I would say Mo’s left foot is better, Cristiano may be better in the air and with his right foot.
“Speed-wise, both are quick and desperate to score goals but I’m not too interested in comparing, sorry.”
However, there is much more talent on show so it may not just come down to those two.
Manchester United manager Ole Gunnar Solskjaer has attempted to play some mind games with who will be available as he said: “It’s still just Friday and the games on Sunday, we’ll give everyone time.
“We might have the whole squad fit, we might be two or three players down.
“Bruno (Fernandes) might be one of them but he’s doing everything he can to be ready.”
It is no surprise that he is attempting it as back in the day Sir Alex Ferguson was great at it.
No one is falling it for it though and it will be no surprise to see Fernandes in the starting eleven which will be a problem for Klopp as he is another player who can turn a game on its head.
Last time out Liverpool were the underdogs at Old Trafford due to their poor from prior to the game and their defensive injury crisis.
Yet Klopp’s side ran riot winning 4-2.
Although that was at an empty stadium.
This time round there will be tens of thousand Manchester United fans howling, booing making it as hostile as it can be for the team that they detest.
Meanwhile the away end will be trying to be as loud as they can be, the noisy neighbours that loathe the home side.
The hatred makes it beautiful.
They will both have a part to play as it can be argued Liverpool sometimes falter and stumble at Old Trafford when the crowd is on their back.
This side is again going for the title though and will need to not let that get to them whilst the Manchester United players could be playing for Solskjaer’s job as they need to prove they have serious title credentials.
Whatever the context the game is always gargantuan.
This time round though there is an extra spice, there is an extra dimension, there is a job on the line with some of the worlds greatest as the main protagonists.
It only makes the spectacle that much better.